元件指南
VectorBuilder提供了許多常用的載體元件,可供用戶在設計載體時(sh自吃í)進(jìn)行選擇。下表按類型提供了這(zhè)些常用元件的詳細信息厭跳。
重鏈恒定區(CH)
姓名 | 描述 | Application Notes | References | 序列 |
---|---|---|---|---|
hlgG1-CH | Human IgG1 heavy c煙國hain constant region | Encodes the constant re公風gion of the human IgG1 hea信鐵vy chain. | Nucleic Acids Res. 10:4071 (1火新982); J Virol. 93:e02270 (2019時呢); | View |
mlgG1-CH | Mouse IgG1 heavy chain cons光購tant region | Encodes the constant region of the mo信的use IgG1 heavy chain. | Proc Natl Acad Sci U S A. 1980 Apr; 77(上數4): 2143–2147. | View |
mlgG2a-CH | Mouse IgG2a heavy chain上著 constant region | Encodes the constant region of the m街要ouse IgG2a heav兒上y chain. | Proc Natl Acad Sci U S A. 78: 4不線495 (1981) | View |
mlgG2b-CH | Mouse IgG2b heav可制y chain constant regi短麗on | Encodes the constant region of the mo跳體use IgG2b heavy chain.討鄉 | Proc Natl Acad Sci U S A商討. 78: 4495 (1981) | View |
輕鏈恒定區(CL)
姓名 | 描述 | Application Note道筆s | References | 序列 |
---|---|---|---|---|
hIgκ-CL | Human immunoglobulin 線見kappa light chain constan裡劇t region | Encodes the constan慢輛t region of the human kappa放鐘 light chain. | Cell. 22(1 Pt 1):197 (1980); Appl Microbiol Biotechnol. 102:5953話看 (2018); J Virol. 93: e02270 (20知學19) | View |
hIgλ2-CL | Human immunoglo湖長bulin lambda 2 light chain consta但信nt region | Encodes the constant region of 在劇the human lambda 2 light chain. | Immunogenetics. 25:63 (1987); J Immunol. 169:27線關1 (2002); Acta Pharm Sin B. 山費9:960 (2019) | View |
mIgκ-CL | Mouse immunoglobulin kappa light c算時hain constant region | Encodes the constant region of the mo雪拿use kappa light chain. | Cell. 22(1 Pt 1):197 (1980); Curr Biol. 25:R820 (2農你015) | View |
mIgλ1-CL | Mouse immunoglobulin lambda 1光拿 light chain constant region | Encodes the constant region of the mou報志se lambda 1 light chain. | Nature. 298:380 (1982) | View |
mIgλ2-CL | Mouse immunoglobulin lambda 2 日來light chain constant region | Encodes the constant region 些船of the mouse lambda 2 light chain. | Nucleic Acids Res. 10:3831 (1飛快982) | View |